Blar i Bergen Open Research Archive på forfatter "Vesterhus, Mette Nåmdal"

Viser treff 1-10 av 10

    • Algebraic topology-based machine learning using MRI predicts outcomes in primary sclerosing cholangitis 

      Singh, Yashbir; Jons, William A.; Eaton, John E.; Vesterhus, Mette Nåmdal; Karlsen, Tom Hemming; Bjørk, Ida; Abildgaard, Andreas; Jørgensen, Kristin Kaasen; Folseraas, Trine; Little, Derek; Gulamhusein, Aliya F.; Petrovic, Kosta; Negård, Anne; Conte, Gian Marco; Sobek, Joseph D.; Jagtap, Jaidip; Venkatesh, Sudhakar K.; Gores, Gregory J.; LaRusso, Nicholas F.; Lazaridis, Konstantinos N.; Erickson, Bradley J. (Journal article; Peer reviewed, 2022)
      Background: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease that can lead to cirrhosis and hepatic decompensation. However, predicting future outcomes in patients with PSC is challenging. Our ...

    • Associations of neopterin and kynurenine–tryptophan ratio with survival in primary sclerosing cholangitis 

      Dhillon, Amandeep Kaur; Rupp, Christian; Bergquist, Annika; Voitl, Robert; Folseraas, Trine; Trøseid, Marius; Midttun, Øivind; Ueland, Per Magne; Karlsen, Tom Hemming; Vesterhus, Mette Nåmdal; Kummen, Martin; Hov, Johannes Espolin Roksund (Journal article; Peer reviewed, 2021)
      Background and aims Biomarkers of inflammation may be of clinical utility in primary sclerosing cholangitis (PSC). We aimed to investigate the interferon gamma-related biomarkers neopterin and kynurenine–tryptophanratio ...

    • Circulating Macrophage Activation Markers Predict Transplant-Free Survival in Patients With Primary Sclerosing Cholangitis 

      Bossen, Lars; Vesterhus, Mette Nåmdal; Hov, Johannes Espolin Roksund; Färkkilä, Martti; Rosenberg, William; Møller, Holger J.; Boberg, Kirsten Muri; Karlsen, Tom Hemming; Grønbæk, Henning (Journal article; Peer reviewed, 2021)
      INTRODUCTION: Primary sclerosing cholangitis (PSC) is a progressive liver disease characterized by bile duct inflammation and fibrosis. The role of macrophages in PSC development and progression is less studied. Macrophage ...

    • Clinical and biochemical impact of vitamin B6 deficiency in primary sclerosing cholangitis before and after liver transplantation 

      Braadland, Peder Rustøen; Bergquist, Annika; Kummen, Martin; Bossen, Lars; Engesæter, Lise Katrine; Reims, Henrik Mikael; Bjørk, Ida Torunn; Grzyb, Krzysztof; Abildgaard, Andreas; Småstuen, Milada Cvancarova; Folseraas, Trine; Trøseid, Marius; Ulvik, Arve; Ueland, Per Magne; Melum, Espen; Line, Pål Dag; Høivik, Marte Lie; Grønbæk, Henning; Karlsen, Tom Hemming; Vesterhus, Mette Nåmdal; Hov, Johannes Espolin Roksund (Journal article; Peer reviewed, 2023)
      Background and aims We previously demonstrated that people with primary sclerosing cholangitis (PSC) had reduced gut microbial capacity to produce active vitamin B6 (pyridoxal 5’-phosphate [PLP]), which corresponded to ...

    • Controlled Attenuation Parameter in Healthy Individuals Aged 8–70 Years 

      Mjelle, Anders Batman; Mulabecirovic, Anesa; Olafsdottir, Edda Jonina; Gilja, Odd Helge; Havre, Roald Flesland; Vesterhus, Mette Nåmdal (Journal article; Peer reviewed, 2021)
      Purpose Controlled attenuation parameter (CAP) is a non-invasive method to assess the presence of liver steatosis. It has been evaluated in children and adults, mainly in either the obese or in subjects with suspected ...

    • Diagnostikk og behandling av autoimmun hepatitt 

      Vesterhus, Mette Nåmdal; Wiencke, Kristine; Haukeland, John Willy; Frigstad, Svein Oskar; Karlsen, Lars Normann; Jørgensen, Kristin Kaasen; Folseraas, Trine (Journal article; Peer reviewed, 2021)
      Autoimmun hepatitt er en kronisk leversykdom som ubehandlet kan føre til levercirrhose og leversvikt. Majoriteten av pasientene responderer godt på standard immunsuppressiv behandling, men noen opplever bivirkninger eller ...

    • Fluctuating biomarkers in primary sclerosing cholangitis: A longitudinal comparison of alkaline phosphatase, liver stiffness, and ELF 

      Fossdal, Guri; Mjelle, Anders Batman; Wiencke, Kristine; Bjørk, Ida Torunn; Gilja, Odd Helge; Folseraas, Trine; Karlsen, Tom Hemming; Rosenberg, William; Melvær, Giil Lasse; Vesterhus, Mette Nåmdal (Journal article; Peer reviewed, 2021)
      Background & Aims Primary sclerosing cholangitis (PSC) is a progressive liver disease characterised by fluctuating liver biochemistries and highly variable disease progression. The Enhanced Liver Fibrosis (ELF®) test and ...

    • Impact on follow-up strategies in patients with primary sclerosing cholangitis 

      Bergquist, Annika; Weismüller, Tobias J.; Levy, Cynthia; Rupp, Christian; Joshi, Deepak; Nayagam, Jeremy Shanika; Montano-Loza, Aldo J.; Lytvyak, Ellina; Wunsch, Ewa; Milkiewicz, Piotr; Zenouzi, Roman; Schramm, Christoph; Cazzagon, Nora; Floreani, Annarosa; Liby, Ingalill Friis; Wiestler, Miriam; Wedemeyer, Heiner; Zhou, Taotao; Strassburg, Christian P.; Rigopoulou, Eirini; Dalekos, George; Narasimman, Manasa; Verhelst, Xavier; Degroote, Helena; Vesterhus, Mette Nåmdal; Kremer, Andreas E.; Bündgens, Bennet; Rorsman, Fredrik; Nilsson, Emma; Jørgensen, Kristin Kaasen; von Seth, Erik; Cornillet Jeannin, Martin; Nyhlin, Nils; Martin, Harry; Kechagias, Stergios; Wiencke, Kristine; Werner, Mårten; Beretta-Piccoli, Benedetta Terziroli; Marzioni, Marco; Isoniemi, Helena; Arola, Johanna; Wefer, Agnes; Söderling, Jonas; Färkkilä, Martti; Lenzen, Henrike (Journal article; Peer reviewed, 2022)
      Background & Aims: Evidence for the benefit of scheduled imaging for early detection of hepatobiliary malignancies in primary sclerosing cholangitis (PSC) is limited. We aimed to compare different follow-up strategies in ...

    • Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma 

      Lapitz, Ainhoa; Azkargorta, Mikel; Milkiewicz, Piotr; Olaizola, Paula; Zhuravleva, Ekaterina; Grimsrud, Marit Mæhle; Schramm, Christoph; Arbelaiz, Ander; O'Rourke, Colm J.; La Casta, Adelaida; Milkiewicz, Malgorzata; Pastor, Tania; Vesterhus, Mette Nåmdal; Jimenez-Agüero, Raul; Dill, Michael T.; Lamarca, Angela; Valle, Juan W.; Macias, Rocio I.R.; Izquierdo-Sanchez, Laura; Pérez Castaño, Ylenia; Caballero-Camino, Francisco Javier; Riaño, Ioana; Krawczyk, Marcin; Ibarra, Cesar; Bustamante, Javier; Nova-Camacho, Luiz M.; Falcon-Perez, Juan M.; Elortza, Felix; Perugorria, Maria J.; Andersen, Jesper B.; Bujanda, Luis; Karlsen, Tom Hemming; Folseraas, Trine; Rodrigues, Pedro M.; Banales, Jesus M. (Journal article; Peer reviewed, 2023)
      Background & Aims Cholangiocarcinoma (CCA), heterogeneous biliary tumours with dismal prognosis, lacks accurate early diagnostic methods especially important for individuals at high-risk (i.e. those with primary sclerosing ...

    • Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing cholangitis 

      Braadland, Peder Rustøen; Schneider, Kai Markus; Bergquist, Annika; Molinaro, Antonio; Lövgren-Sandblom, Anita; Henricsson, Marcus; Karlsen, Tom Hemming; Vesterhus, Mette Nåmdal; Trautwein, Christian; Hov, Johannes Espolin Roksund; Marschall, Hanns-Ulrich (Journal article; Peer reviewed, 2022)
      Background & Aims: Farnesoid X receptor (FXR) agonists and fibroblast growth factor 19 (FGF19) analogues suppress bile acid synthesis and are being investigated for their potential therapeutic efficacy in cholestatic liver ...